Thursday, 7 May 2015

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Etizolam (trade names Etilaam, Etizest) is a short-acting psychoactive drug of the thienodiazepine class which has been shown to produce depressant, anxiolytic, sedative, hypnotic, muscle relaxant, anticonvulsant, and amnestic effects. Etizolam, like benzodiazepines, binds to modulatory sites on the GABA gamma-aminobutyric acid receptors. Etizolam is not commonly prescribed and is not recognised as a controlled substance in many parts of the world, leading to its rise in popularity as a product of many research chemical vendors.
Etizolam has a relatively fast onset of action and symptomatic relief. 1 - 2 mg of Etizolam is of similar potency to 10mg Diazepam. For anxiety disorders associated with depression, 1 mg can be administered several times over the course of a day. Smaller doses may alleviate symptoms of panic, and it can be used before bed for relief of insomnia.


  • 1 Chemistry
  • 2 Pharmacology
  • 3 Subjective effects
    • 3.1 Physical Effects
    • 3.2 Cognitive Effects
  • 4 Toxicity and harm potential
    • 4.1 Lethal dosage
    • 4.2 Tolerance and addiction potential
  • 5 Legal issues
  • 6 See also
  • 7 References


Etizolam is a structural relative of benzodiazepines, where by the benzene ring has been replaced by a thiophene ring, classifying it as a thienodiazepine. It is classed as a research chemical.


Benzodiazepines produce a variety of effects by binding to the benzodiazepine receptor site and magnifying the efficiency and effects of the neurotransmitter gamma aminobutyric acid (GABA) by acting on its receptors.[1] As this site is the most prolific inhibitory receptor within the brain its modulation results in the sedating (or calming effects) of etizolam on the nervous system.

Subjective effects

The effects listed below are based upon the subjective effects index and personal experiences of PsychonautWiki contributors. The listed effects will rarely if ever occur all at once but heavier dosages will increase the chances and are more likely to induce a full range of effects.

Physical Effects

The physical effects of Etizolam can be broken down into 5 components all of which progressively intensify proportional to dosage. These are described below and generally include:

  • Sedation - In terms of energy level alterations, Etizolam is extremely sedating and often results in an overwhelmingly lethargic state. At higher levels, this causes users to suddenly feel as if they are extremely sleep deprived and have not slept for days, forcing them to sit down and generally feel as if they are constantly on the verge of passing out instead of engaging in physical activities. This sense of sleep deprivation increases proportional to dosage and eventually becomes powerful enough to force a person into complete unconsciousness.

  • Respiratory depression

  • Muscle relaxation

  • Dizziness

  • Motor control loss

Cognitive Effects

The cognitive effects of Etizolam can be broken down into 7 components all of which progressively intensify proportional to dosage. The general head space of Etizolam is described by many as one of intense sedation and decreased inhibition. It contains a large number of typical depressant cognitive effects.
The most prominent of these cognitive effects generally include:

  • Amnesia

  • Anxiety suppression

  • Thought deceleration

  • Disinhibition

  • Information processing suppression

  • Euphoria

  • Compulsive redosing

Toxicity and harm potential

  • Blepharospasms (twitching eyelid) can occur with long term use.
  • Rarely, Erythema annulare centrifugum skin lesions have been reported.

Lethal dosage

The lethal dosage of Etizolam has not been established, however like many benzodiazepines it has a large therapeutic index and margin of safety. Complications may arise when administered in excess. Intentional overdoses have been reported.
As with all GABAergic drugs, overdose can be lethal when mixed with other depressants including alcohol or opioids.

Tolerance and addiction potential

Tolerance will develop to the sedative-hypnotic effects within a couple of days of repeated administration. Abrupt discontinuation of Etizolam, following regular dosing over several days, can result in a withdrawal phase which includes rebound symptoms such as increased anxiety and insomnia. It is possible to gradually reduce the dose over the course of several days, which will lengthen the duration of the withdrawal period, but reduce the perceived intensity.
Thienodiazepine discontinuation is notoriously difficult; it is potentially life threatening for individuals using regularly to discontinue use without tapering their dose over a period of weeks. There is an increased risk of seizure following discontinuation of Etizolam. Drugs which lower the seizure threshold such as tramadol should be avoided during withdrawal.

Legal issues

  • United States August 2014 A Connecticut man was charge with IV count's possession of Etizolam after being involved with a DUI[2] In the same month the state of Arkansas listed Etizolam as a Schedule I drug under their drug scheduling guidelines.[3]
  • Germany: Phenazepam and Etizolam were controlled in Germany in July 2013.[4][5]
  • Poland: Etizolam may be scheduled under the Act on Counteracting Drug Addiction and the State Sanitary Inspection -Article 27c.
  • United Kingdom: Etizolam is not controlled as of July 2013.

Buy Etizolam

How to find Etizolam

Etizolam is a benzodiazepine analogue that's a powerful component for anyone suffering with anxiety and sleeplessness disorders. Etizolam can also be a legal product that will be sold to educational institutions and research facilities for research purposes.

Purchasing the merchandise could be carried out lawfully online.

While this might seem obvious, there are really so many "fly by night" companies that encourage the exact same products, nevertheless they can be made from inferior quality, that may undermine all of the research you're doing.

This is the reason why it is wise to select a number of businesses which you find online and then begin your assignments, reviewing each one and comparing them narrowing down your list to get the ideal provider you could establish a long lasting relationship that is working with.

You must make sure you're buying from a reputable provider that has an excellent name in the market when you get the research chemical Etizolam online. You would like them to be trustworthy, furnish a lot of distinct research products and offer customer care that is exceptional.

The web is brimming with businesses for one to select from, therefore it is rewarding deciding on some of businesses to begin going through. Along with your list in hand, you may need to spend time going through the web site of each one, seeing what products they provide, costs and their delivery times. Because you may possess a budget you're working, this might allow you to narrow down your search somewhat to.

The grade of the item is more significant, particularly to help your research while a reasonable cost can be an enormous advantage for you.

You might want to pick up the telephone and provide them a call once you've some indication on what each firm offers, as well as their delivery times. It consistently provides some reassurance when you talk and telephone to some actual individual on the opposite side of the telephone. In addition, it gives a chance to learn their professionalism and customer service to you, the way in which they ensure you're given the very best customer experience and how readily they answer any questions you might have.

With this particular achieved, you could be down to two firms to select from. Now's the time to learn what previous customers must say. A good option to do so is on-line. Kind in the company name and undergo the outcomes. You are searching for newsgroups and review sites where it's possible for you to read on actual customer views, this could allow you to finish your search leaving one firm that can give you the Etizolam you want moving forward to you.

Make sure you make your purchase and also enroll online. It is wise to select a bank card, by doing this you might be offered protection that is added, particularly on your first order.